News

Hirnperfusion & Parkinson: Eine entscheidende Verbindung

Die Parkinson-Krankheit (Morbus Parkinson) ist eine fortschreitende neurodegenerative Erkrankung. Das Verständnis der Durchblutung des Gehirns ist entscheidend für eine bessere Diagnose und Behandlung. Arterial Spin Labeling (ASL) MRT, eine nicht-invasive Perfusionsbildgebung, liefert wertvolle Einblicke durch die Messung des zerebralen Blutflusses.

Früherkennung – Erkennt Perfusionsveränderungen, noch bevor deutliche Symptome auftreten.
Verlaufsbeobachtung – Überwacht die Durchblutungsreduktion in betroffenen Hirnregionen.
Therapieoptimierung – Unterstützt die Bewertung der Wirksamkeit von Behandlungen und die Personalisierung der Versorgung.
Forschungsförderung – Hilft bei der Medikamentenentwicklung und beim tieferen Verständnis der Parkinson-Pathologie.

ASL-MRT revolutioniert die Art und Weise, wie wir Parkinson erkennen, überwachen und behandeln – und ebnet den Weg für präzisere und wirksamere Interventionen.

Bei mediri GmbH unterstützen wir Sie mit hochentwickelten, aber benutzerfreundlichen ASL-Bildanalyse-Tools – einschließlich spezialisierter ASL-Sequenzen zur Messung der Austauschzeit. Unser Service deckt alle Aspekte der ASL-Bildgebung ab.

An diesem Weltgesundheitstag betonen wir die Bedeutung einer hochwertigen Gesundheitsversorgung für Frauen – vor, während und nach Schwangerschaft und Geburt. Die Gesundheit von Frauen ist ein Grundpfeiler für starke Familien und lebendige Gemeinschaften.

Bei mediri sind wir stolz darauf, ein Arbeitgeber zu sein, der sich für die Gesundheit und das Wohlbefinden unserer Mitarbeiterinnen einsetzt. Wir engagieren uns für ein unterstützendes Arbeitsumfeld, das ihre Gesundheit fördert.

Lasst uns gemeinsam dafür sorgen, dass jede Frau die Fürsorge erhält, die sie verdient. Gemeinsam schaffen wir eine gesündere Welt!

Arterial Spin Labeling (ASL) ist eine moderne MRT-Technik zur Messung der Perfusion. Dabei wird die Magnetisierung von Wasserstoffprotonen im Blut verändert, sodass sie als natürliche Tracer dienen können. Diese Methode ist vollständig nicht-invasiv und kommt ohne ionisierende Strahlung oder externe Kontrastmittel aus.

Die nicht-invasive Natur von ASL bietet zahlreiche Vorteile für die klinische Forschung: Sie ermöglicht wiederholte Messungen des zerebralen Blutflusses (CBF) – so oft wie nötig – und ist besonders geeignet für empfindliche Patientengruppen, wie Menschen mit Niereninsuffizienz oder Kinder.

ASL bietet eine sichere und effektive Möglichkeit zur Messung der Hirnperfusion und ist daher ideal für verschiedenste klinische Anwendungen.

Are you interested in truly non-invasive BBB imaging? We are. That’s why we are investigating in Multi-Echo Arterial Spin Labeling MR imaging techniques (a.k.a. BBB ASL) that enable Tex brain maps.

If you are using ASL sequences for your research you will be familiar with CBF and ATT maps. Our cutting-edge MR sequences together with sophisticated mathematical models go beyond these and produce Tex maps, which show the microvascular exchange dynamics and promise to be an indicator for BBB integrity.

More research in this field is to come and will show how Tex can be used clinically in the future. Be part of this research: Contact us if you want to join us on this exciting journey! 

Not (yet) familiar with the wording? Here you go:

ASL Arterial Spin Labeling is a special MRI technique which uses magnetically labeled blood for perfusion measurements.
BBB Blood Brain Barrier… you have heard of that one.
CBF Cerebral Blood Flow is a measure for brain perfusion.
ATT Arterial Transit Time is the time taken from blood to travel from large arteries in the neck to the cerebral tissue.
Tex exchange Time serves as proxy for BBB permeability to water.

Meet our COO Dr. Julia Müller in Frankfurt to discuss hot topics in Neuroimaging from Perfusion to BBB integrity.
How can we bring perfusion MRI into clinical application? How can we simplify the analysis of Arterial Spin Labeling MR images and provide sophistaced biomarkers for brain perfusion and micro-architecture? I am looking forward to discuss these topics with you at the DGKN e.V. Conference in Frankfurt this week.

Meet our CEO Prof. Dr. Matthias Günther at ISMRM in Pamplona, Spain! 

Join us from 15-17 March 2025 at the ISMRM Workshop on Perfusion MRI and engage with our CEO, Prof. Dr. Matthias Günther. This workshop aims to disseminate cutting-edge research on perfusion MRI and related methods.

Engineers, scientists, and clinicians interested in perfusion MRI techniques and applications, from acquisition to processing strategies, are welcome to join us. Don’t miss this opportunity to connect and learn from the best in the field!

mediri is your dedicated partner for efficient and reliable imaging studies. As your one-stop shop, we provide everything you need – from planning to central read – all under one roof. Benefit from our unique combination of study experience and cutting-edge technological expertise. Our mTRIAL cloud platform enables seamless data exchange, maximum data security in Germany and AI-supported workflows tailored to your study.

At mediri, we are committed to providing exceptional support to our customers and partners. Whether you are seeking expert advice on your imaging study, have questions about medical imaging, or need detailed information about our software solution, mTRIAL, our dedicated team is here to assist you.

We offer:
– Personalized consultations to guide you through your imaging studies
– Expert insights into all aspects of medical imaging
– Comprehensive support for our mTRIAL image data management system

Your success is our top priority, and we are here to ensure you achieve your goals.

…but we also collect other image data and reports from the study sites.

At mediri, we are proud to be at the forefront of medical imaging and clinical imaging trials. Our deep expertise in DICOM (Digital Imaging and Communications in Medicine) and other imaging data formats ensures that we provide comprehensive and seamless support to our study sites.

We are specialized in collecting, managing, and analyzing a wide range of image data and reports from various study sites. This meticulous approach allows us to drive innovation and excellence in medical research, ensuring that our findings are both accurate and impactful.

Our commitment to advancing healthcare through cutting-edge technology and dedicated research is unwavering. By leveraging our extensive knowledge and state-of-the-art tools, we aim to make significant contributions to the medical field.

Since 2004 we have been your trusted service provider for medical image data management in clinical studies. Join us on our journey to transform healthcare and improve patient outcomes.

Exciting times at EUCROF25 Conference!
Our COO, Julia Müller, recently attended the EUCROF Conference in Copenhagen. This fantastic event featured insightful presentations and a wealth of rich topics, particularly on the evolving landscape of Decentralized Clinical Trials (DCTs). It also provided an excellent opportunity to connect with wonderful people.

From discussing the latest trends in clinical research to networking with industry leaders, the conference provided a fantastic platform for knowledge exchange and collaboration. We are excited to bring these new insights back to our team and continue driving innovation in our field.
A big thank you to the organizers and all the participants for making this event a success!
Looking forward to the next one in Amsterdam.

Today we unite for World Cancer Day. This year’s theme, „United by Unique,“ underscores the importance of personalized cancer care. Cancer is more than a diagnosis; it’s a personal journey of resilience and hope. Let’s raise awareness, support those battling cancer, and advocate for equitable access to treatments. Together, we can make a difference.

At mediri, we are partners in oncological clinical trials that require meticulous image data acquisition and quality assurance. Our Collect & Hold services offer image collection, quality checks, site support, and project management tailored to early-phase studies. These services are ideal for trials requiring longitudinal imaging data or integrating centralized reviews. We help you achieve the best outcomes for all stakeholders in your study.