mri

Next up in our mTRIAL release preview:
the Unidirectional Feature for RECIST MRI — a key advancement in longitudinal lesion tracking and precision oncology.

Users can now measure lesion diameters with pinpoint accuracy, activate a second viewing window to compare follow-up exams, and adjust views to assess additional lesions — all within one streamlined workflow. Seamless transitions between examinations make longitudinal analysis faster and more intuitive than ever.

We are thrilled about the market approval of Lecanemab in the EU, marking a promising breakthrough for millions affected by Alzheimer’s disease. Early detection is crucial, and in this field, our ASL team is at the forefront of research. Upcoming observational studies can be supported by our cutting-edge technology, which can non-invasively monitor the course of the disease.

Arterial Spin Labeling (ASL) represents a modern MRI technique for measuring regional brain perfusion and permeability by modifying the magnetization of blood water protons to serve as natural tracers. This method is entirely non-invasive, eliminating the need for ionizing radiation or external contrast agents.

The non-invasive nature of ASL provides numerous benefits for clinical research: it allows for repeated cerebral blood flow (CBF) measurements as often as needed and is suitable for use in vulnerable groups, such as patients with renal failure, elderly individuals or Alzheimer’s patients.

Brain Perfusion & Parkinson’s: A Vital Connection

Parkinson’s disease (PD) is a progressive neurodegenerative disorder, and understanding brain blood flow is key to improving diagnosis and treatment. Arterial Spin Labeling (ASL) MRI, a non-invasive perfusion imaging technique, provides valuable insights by measuring cerebral blood flow.

Early Detection – Identifies perfusion changes before significant symptoms appear.
Tracking Disease Progression – Monitors blood flow reductions in affected brain regions.
Optimizing Treatment – Helps assess therapy effectiveness and personalize care.
Advancing Research – Aids in drug development and deeper understanding of PD pathology.

ASL MRI is revolutionizing how we detect, monitor, and treat Parkinson’s, paving the way for more precise and effective interventions.

At mediri GmbH, we support you with sophisticated yet easy-to-use ASL image analysis tools, including specialized ASL sequences that can measure exchange time. Our services cover all aspects of ASL imaging.
As a one-stop-shop, we provide comprehensive evaluation services. We specialize in clinical trials that demand precise image data acquisition and quality assurance. Our services include image collection, quality checks, site support, and project management. Perfect for clinical trials requiring longitudinal imaging data or centralized reviews.

Arterial Spin Labeling (ASL) represents a modern MRI technique for measuring perfusion, which modifies the magnetization of blood water protons to serve as natural tracers.
This method is entirely non-invasive, eliminating the need for ionizing radiation or external contrast agents.
The non-invasive nature of ASL provides numerous benefits for clinical research: it allows for repeated cerebral blood flow (CBF) measurements as often as needed and is suitable for use in vulnerable groups, such as patients with renal failure or pediatric patients.

Why It Matters: ASL offers a safe and effective way to measure cerebral perfusion, making it ideal for various clinical applications.

Have you heard about ASL before? Share your thoughts and experiences with us!

Meet our COO Dr. Julia Müller in Frankfurt to discuss hot topics in Neuroimaging from Perfusion to BBB integrity.
How can we bring perfusion MRI into clinical application? How can we simplify the analysis of Arterial Spin Labeling MR images and provide sophistaced biomarkers for brain perfusion and micro-architecture? I am looking forward to discuss these topics with you at the DGKN e.V. Conference in Frankfurt this week.

Meet our CEO Prof. Dr. Matthias Günther at ISMRM in Pamplona, Spain! 

Join us from 15-17 March 2025 at the ISMRM Workshop on Perfusion MRI and engage with our CEO, Prof. Dr. Matthias Günther. This workshop aims to disseminate cutting-edge research on perfusion MRI and related methods.

Engineers, scientists, and clinicians interested in perfusion MRI techniques and applications, from acquisition to processing strategies, are welcome to join us. Don’t miss this opportunity to connect and learn from the best in the field!

mediri is your dedicated partner for efficient and reliable imaging studies. As your one-stop shop, we provide everything you need – from planning to central read – all under one roof. Benefit from our unique combination of study experience and cutting-edge technological expertise. Our mTRIAL cloud platform enables seamless data exchange, maximum data security in Germany and AI-supported workflows tailored to your study.

…but we also collect other image data and reports from the study sites.

At mediri, we are proud to be at the forefront of medical imaging and clinical imaging trials. Our deep expertise in DICOM (Digital Imaging and Communications in Medicine) and other imaging data formats ensures that we provide comprehensive and seamless support to our study sites.

We are specialized in collecting, managing, and analyzing a wide range of image data and reports from various study sites. This meticulous approach allows us to drive innovation and excellence in medical research, ensuring that our findings are both accurate and impactful.

Our commitment to advancing healthcare through cutting-edge technology and dedicated research is unwavering. By leveraging our extensive knowledge and state-of-the-art tools, we aim to make significant contributions to the medical field.

Since 2004 we have been your trusted service provider for medical image data management in clinical studies. Join us on our journey to transform healthcare and improve patient outcomes.

Your Challenge: Managing diverse measurement needs in clinical trials without compromising accuracy or time.
Our Solution: Diverse measurement tools—including linear, cross-sectional, freehand, and semi-automatic measurements—all in one platform.
Your Gain: Accuracy and flexibility, enabling reviewers to focus on what truly matters—delivering high-quality insights.
Empowering radiologists with tools that match their expertise.

Stop sending CDs with image data all over the world. Simply upload your medical images via web browser to the central study server – with automatic pseudonymization before upload.
Our study servers are hosted in Germany and comply to BSI C5 standard.
mediri’s image data management software mTRIAL covers the complete workflow of a clinical study from upload to central read and reporting. All stakeholders of a project have real-time access to the image data base. This way we make clinical studies more efficent and secure.

Just imagine…you are planning a multi-center imaging study and you can choose whichever site you want irrespective of the MR scanner they have. In SIMAB, Fraunhofer MEVIS and mediri GmbH are developing a vendor-agnostic MR sequence development framework to increase the comparability of imaging biomarkers regardless of the employed scanner equipment.
Structural imaging biomarkers as brain atrophy or lesions will be assessed as well as functional indicators of neurological diseases, e.g. brain perfusion or permeability.
SIMAB is funded by the German Ministry for Research and Education.