mannheim

Did you know that Parkinson’s disease is the fastest-growing brain disease? At the same time, Parkinson’s disease is so variable, almost no 2 individuals’ symptoms and progression are the same. That is why at mediri, we are working every day to improve the diagnosis and therapy of Parkinson’s disease using advanced MR Imaging and Focused Ultrasound techniques.

For more details, you can have a look at this publication on automatic planning of MR-guided transcranial focused ultrasound treatment or this review article on blood-brain barrier dysfunction imaging.

We proudly announce that mediri has once again received the Digital Innovator 2024 award from CHIP in the category ”medical technology“.
In times of digitization, CHIP and data analysis specialist Globis Consulting have studied the innovative power of German companies and institutes in digitization. CHIP is known as one of the top recommended brands. See the full ranking here.

Recently, a newspaper article about our project BOSOMSHIELD got mentioned in the newspaper echo-online. If you want to know more about the importance of our work and how we want to improve the field of breast cancer, you can read the article down below. 

Today is International Day of Radiology to promote the seismic impact of radiology on medicine – earlier detection, fewer surgeries, and game-changing treatment outcomes. Analyzing radiological images in multi centric clinical studies can be challenging considering standardization and patient data privacy.
Mediri is constantly evolving its image data management platform mTRIAL for secure and reliable central reads in clinical studies. Currently, mTRIAL is getting ready for RANO 2.0 evaluation of low- and high-grade gliomas according to the recently published update by Wen et al. Stay posted.

RANO 2.0: Update to the Response Assessment in Neuro-Oncology Criteria for High- and Low-Grade Gliomas in Adults | Journal of Clinical Oncology (ascopubs.org)

New office. New Neighbours. New view.
It’s done! We have offically moved to Am Taubenfeld 21/1 in 69123 Heidelberg.

These numbers again stress the importance of research in breast cancer detection and relapse prediction. We are proud to be part of the Marie-Sklodowska Curie network bosomshield.eu aiming at the combination of clinical, pathological and radiological data for better treatment and therapies. Still, early detection of breast cancer is one of the most important factors for successfull treatment, so be mindful and take care of yourself!

World Alzheimer’s Day is a global effort to raise awareness and challenge the stigma around Alzheimer’s disease and other dementia. Do you know the differences between Alzheimer’s and dementia?
Dementia is a general term for a decline in mental ability severe enough to interfere with daily life. Alzheimer’s is one of several potential reasons for this decline, among them Frontotemporal Dementia, Huntington’s Disease, Parkinsons’s, or Vascular Dementia. Functional brain imaging is a cornerstone for the differentiation between all these different types of dementia and can support patient management as well as the research for potential therapies.
Perfusion imaging with Arterial Spin Labeling MRI has the potential to differentiate between Alzheimer’s and FTD but lacks standardization. In the ASPIRE project we develop an easy-to-use ASL evaluation tool that helps physicians to compare the brain perfusion pattern of a patient to a healthy control group. For more information visit aspire-mri.eu and alz.org.

Many thanks to Marylène Lejeune and Carlos López Pablo at Hospital Verge da la Cinta in Tortosa for hosting our PhD Candidate Yaqeen Ali for his first secondment within the BosomShield project. Yaqeen now knows a lot more about histopathologic imaging and will work on integrating these images into mTRIAL for AI-supported prediction of breast cancer relapse probability.

Click here for more information on this project: https://bosomshield.eu/

Have you read one of the latest publications on iron rim lesions in multiple sclerosis by our research partners at the Universitätsmedizin Mannheim? The authors around Prof. Achim Gass conclude that iron rim lesions are associated with higher intrathecal immunoglobin G synthesis. Furthermore, CSF-mediated intrathecal smouldering inflammation could explain a CSF-related gradient of tissue damage.
Read the publication here.

Have you ever thought about assessing cerebral perfusion non-invasively in your next clinical trial? If so, this recently published review paper will address the most important questions such as how to equalize data acquisition across sites, how to perform QC and process the data. 
Read more here: https://lnkd.in/gE3Z8BKT